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140 (Table 2) It is increasingly recognized that disturbances in urate transport, both in the gastrointestinal tract and kidneys, are pivotal in the pathogenesis of diseases associated with hyperuricemia

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Symptoms of glutathione synthetase deficiency may include: Seizures Hampered reaction to speech and physical stimuli Poor coordination Intellectual disability Vulnerability to bacterial infections Low glutathione levels are also associated with a large number of disorders, including some types of cancer and AIDS

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